Member
Associate Professor (Lecturer)
Dr. Hideaki Takano
Career
| Mar. 2015 | B. S. in School of Advanced Science and Engineering, Waseda University |
|---|---|
| Mar. 2017 | M. S. in Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University (Supervisor: Prof. Takanori Shibata) |
| Apr. 2018–Mar. 2019 | University of Cambridge, Visiting Student (Overseas Challenge Program for Young Researchers of JSPS, Supervisor: Prof. Robert J. Phipps) |
| Apr. 2018–Mar. 2020 | Research Fellow of the JSPS (DC2) |
| Mar. 2020 | Ph. D. in Scince, Waseda University |
| Apr. 2020–Sep. 2021 | Postdoctoral Researcher, WPI-ICReDD, Hokkaido University (JST-ERATO Maeda Artificial intelligence for Chemical Reaction Design and Discovery Project) |
| Oct. 2021–Nov. 2022 | Specially Appointed Assistant Professor, WPI-ICReDD, Hokkaido University (JST-ERATO Maeda Artificial intelligence for Chemical Reaction Design and Discovery Project) |
| Dec. 2022– | Assistant Professor, Institute for Advanced Research and Graduate School of Engineering, Nagoya University |
| Dec. 2022– | Leading Initiative for Excellent Young Researchers, JSPS |
Achievements
| CV | |
|---|---|
| ORCiD | 0000-0002-0466-0116 |
| ResearcherID | N-6736-2018 |
| researchmap | 70823277 |
Field
Organic Chemistry, Reaction Organic Chemistry, Computational Chemistry
Original Papers
30. Bowl-Shaped Anthracene-Fused Antiaromatic Ni(II) Norcorrole: Synthesis, Structure, Assembly with C60, and Photothermal Conversion
K. Wang, A. Ghosh, D. Shimizu, H. Takano, M. Ishida, R. Kishi, H. Shinokubo.
Angew. Chem. Int. Ed. 2024, 63, e202419289.
29. Zig-zag-fused π-extended BODIPYs via gold-catalysed cycloisomerisation
F. Ohashi, H. Takano*, H. Shinokubo*
Chem. Commun. 2024, 60, 12892–12895.
28. Strain-Releasing Ring-Opening Diphosphinations for the Synthesis of Diphosphine Ligands with Cyclic Backbones
C. G. Krishnan, H. Takano, H. Katsuyama, W. Kanna, H. Hayashi, T. Mita*
JACS Au 2024, 4, 3777–3787.
Press Release (English)
Selected as Cover Picture
27. Radical reactivity of antiaromatic Ni(II) norcorroles with azo radical initiators
S. A. Shafie, R. Nozawa, H. Takano, H. Shinokubo*
Beilstein J. Org. Chem. 2024, 20, 1967–1972.
26. Syntheses of Thiophene–Thiophene-Linked Corrorin Dimers with Tunable Near-Infrared Absorption and Distinctive Reactivity
Y. Xu, B. Zhu, L. Zhang, G. Baryshnikov, F. Sha, E. Nishimoto, H. Takano, C. Li, X. Wu, H. Ågren, H. Shinokubo, Y. Xie*, Q. Li*
Org. Lett. 2024, 26, 571–576.
25. Synthesis of Bicyclo[1.1.1]pentane (BCP)-Based Straight-Shaped Diphosphine Ligands
H. Takano, H. Katsuyama, H. Hayashi, M. Harukawa, M. Tsurui, S. Shoji, Y. Hasegawa, S. Maeda, T. Mita*
Angew. Chem. Int. Ed. 2023, Early View, e202303435.
Press Release (English)
24. Photoredox/HAT-Catalyzed Dearomative Nucleophilic Addition of the CO2 Radical Anion to (Hetero)Aromatics
S. R. Mangaonkar, H. Hayashi, H. Takano, W. Kanna, S. Maeda, T. Mita*
ACS Catal. 2023, 13, 2482-2488.
Press Release (English)
23. Prediction of High-Yielding Single-Step or Cascade Pericyclic Reactions for the Synthesis of Complex Synthetic Targets
T. Mita,* H. Takano, H. Hayashi, W. Kanna, Y. Harabuchi, K. N. Houk, S. Maeda
J. Am. Chem. Soc. 2022, 50, 22985-23000.
Press Release (English)
JACS Spotlight
Selected as Cover Picture
Science Blog, In the pipeline
22. Oxidation and Reduction Pathways in the Knowles Hydroamination via a Photoredox‐Catalyzed Radical Reaction
Y. Harabuchi, H. Hayashi, H. Takano, T. Mita, S. Maeda
Angew. Chem. Int. Ed. 2023, 62, e202211936.
Press Release (English)
21. A theory-driven synthesis of symmetric and unsymmetric 1,2-bis(diphenylphosphino)ethane analogues via radical difunctionalization of ethylene
H. Takano, H. Katsuyama, H. Hayashi, W. Kanna, Y. Harabuchi, S. Maeda, T. Mita
Nat. Commun. 2022, 13, 7034.
Press Release (English)
Nature Portfolio, Behind the Paper
Chem-Station Spotlight Research
20. Experimental and Theoretical Evidence for Relativistic Catalytic Activity in C–H Activation of N-Phenylbenzamide Using a Cationic Iridium Complex
C. Takashima, H. Kurita, H. Takano, Y. Ikabata, T. Shibata, H. Nakai
J. Phys. Chem. A 2022, 126, 7627-7638.
19. In silico reaction screening with difluorocarbene for N-difluoroalkylative dearomatization of pyridines
H. Hayashi, H. Katsuyama, H. Takano, Y. Harabuchi, S. Maeda,* T. Mita*
Nat. Synth. 2022, 1, 804-814.
Press Release (English)
Nature Synthesis Research Briefing
Chem-Station Spotlight Research
18. Electrochemical Dearomative Dicarboxylation of Heterocycles with Highly Negative Reduction Potentials
Y. You, W. Kanna, H. Takano, H. Hayashi, S. Maeda,* T. Mita*
J. Am. Chem. Soc. 2021, 144, 3685-3695.
Press Release (English)
17. Radical Difunctionalization of Gaseous Ethylene Guided by Quantum Chemical Calculations: Selective Incorporation of Two Molecules of Ethylene
H. Takano, Y. You, H. Hayashi, Y. Harabuchi, S. Maeda,* T. Mita*
ACS Omega 2021, 6, 33846-33854.
16. Carboxylation of a Palladacycle Formed via C(sp3)–H Activation: Theory‐Driven Reaction Design
W. Kanna, Y. Harabuchi, H. Takano, H. Hayashi, S. Maeda,* T. Mita*
Chem. Asian J. 2021, 16, 4072-4080.
15. Synthesis of Difluoroglycine Derivatives from Amines, Difluorocarbene, and CO 2 : Computational Design, Scope, and Applications
H. Hayashi, H. Takano, H. Katsuyama, Y. Harabuchi, S. Maeda,* T. Mita*
Chem. Eur. J. 2021, 27, 10040-10047.
Selected as Front Cover
14. Pt(II)-Chiral Diene-Catalyzed Enantioselective Formal [4+2] Cycloaddition Initiated by C-C Bond Cleavage and Elucidation of a Pt(II)/(IV) Cycle by DFT Calculations
T. Shibata,* N. Shiozawa, S. Nishibe, H. Takano, S. Maeda*
Org. Chem. Front. 2021, 8, 6985-6991.
13. Gold-catalyzed dual C–C bond cleavage of biphenylenes bearing a pendant alkyne at ambient temperature
H. Takano, S. Okazaki, S. Nishibe, T. Ito, N. Shiozawa, N. Sugimura, K. S. Kanyiva, T. Shibata*
Org. Biomol. Chem. 2020, 18, 5826-5831.
12. Catalytic Enantioselective Synthesis of Axially Chiral Polycyclic Aromatic Hydrocarbons (PAHs) via Regioselective C-C Bond Activation of Biphenylenes
H. Takano, N. Shiozawa, Y. Imai, K. S. Kanyiva, T. Shibata*
J. Am. Chem. Soc. 2020, 142, 4714-4722.
Chem-Station Spotlight Research
Selected as a cover picture(Vol. 142, Issue 16)
11. Relativistic Effect on Homogeneous Catalytic Reaction by Cationic Iridium Catalysts
C. Takashima, Y. Ikabata, H. Kurita, H. Takano, T. Shibata, H. Nakai*
J. Comput. Chem. Japan 2019, 18, 136-138.
10. Consecutive HDDA and TDDA reactions of silicon-tethered tetraynes for the synthesis of dibenzosilole-fused polycyclic compounds and their unique reactivity
A. Mitake, R. Nagai, A. Sekine, H. Takano, N. Sugimura, K. S. Kanyiva, T. Shibata*
Chem. Sci. 2019, 10, 6715-6720.
9. Enantioselective Synthesis of Nine- to Eleven-Membered Cyclic Polyphenylenes Containing Heteroatoms by Catalytic Intramolecular [2+2+2] Cycloaddition
T. Shibata,* T. Fusamae, H. Takano, N. Sugimura, K. S. Kanyiva
Asian. J. Org. Chem. 2019, 8, 970-977.
8. Regioselective Activation of a Sterically More Hindered C-C Bond of Biphenylenes Using an Alkene as Both a Directing Group and a Reaction Moiety
H. Takano, T. Ito, K. S. Kanyiva, T. Shibata*
Chem. Eur. J. 2018, 24, 15173-15177.
Selected as Hot Paper
Selected as Cover Feature7. α-Amino Acid Sulfonamides as Versatile Sulfonylation Reagents: Silver-Catalyzed Synthesis of Coumarins and Oxindoles by Radical Cyclization
K. S. Kanyiva,* D. Hamada, S. Makino,H. Takano, T. Shibata*
Eur. J. Org. Chem. 2018, 83, 5905-5909.
Selected as Very Important Paper
Selected as Front Cover6. A Ir-Catalyzed Synthesis of Substituted Tribenzosilepins by Dehydrogenative C–H/Si–H Coupling
T. Shibata,* N. Uno, T. Sasaki, H. Takano, T. Sato, K. S. Kanyiva
J. Org. Chem. 2018, 83, 3426-3432.
5. DFT Studies on the Mechanism of the Iridium-Catalyzed Formal [4 + 1] Cycloaddition of Biphenylene with Alkenes
H. Takano, N. Sugimura, K. S. Kanyiva, T. Shibata*
ACS Omega 2017, 2, 5228-5234.
4. Intramolecular C-H Alkenylation of N-Alkynylindoles: Exo and Endo Selective Cyclization by the Choice of Metal Catalysts
T. Shibata,* T. Baba, H. Takano, K. S. Kanyiva
Adv. Synth. Catal. 2017, 359, 1849-1853.
Selected as Very Important Publication
3. Iridium-Catalyzed Formal [4+1] Cycloaddition of Biphenylenes with Alkenes Initiated by C-C Bond Cleavage for the Synthesis of 9,9-Disubstituted Fluorenes
H. Takano, K. S. Kanyiva, T. Shibata,*
Org. Lett. 2016, 18, 1860-1863.
2. Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates
T. Shibata,* N. Ryu, H. Takano
Adv. Synth. Catal. 2015, 357, 1131-1135.
1. Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates
T. Shibata,* H. Takano
Org. Chem. Front. 2015, 2, 383-387.
Selected as Very Important Publication
Selected as Inside CoverAccounts and Reviews
3. AFIR method-guided organic synthesis: Development of radical functionalization of ethylene
H. Takano
Japan Society of Theoretical Chemistry, Frontier 2022, 4, 212-218.
2. Versatile Transformations of Biphenylenes by Transition-Metal Catalysts and Application for the Synthesis of Polycyclic Hydrocarbons
H. Takano, T. Shibata
J. Syn. Org. Chem. Jpn. 2021, 79, 849-858.
