Member忍久保研の構成員
助教：髙野 秀明
Dr. Hideaki Takano
略歴
| 2015年3月 | 早稲田大学 先進理工学部 化学・生命化学科 卒業 |
|---|---|
| 2017年3月 | 早稲田大学大学院 先進理工学研究科 化学・生命化学専攻修士課程 修了 (指導教官：柴田 高範 教授） |
| 2018年4月–2019年3月 | University of Cambridge, Visiting Student (若手研究者海外挑戦プログラム, 受入研究者：Prof. Robert J. Phipps) |
| 2018年4月–2020年3月 | 日本学術振興会特別研究員(DC2) |
| 2020年3月 | 早稲田大学大学院 先進理工学研究科 化学・生命化学専攻博士課程 修了 (指導教官：柴田 高範 教授） 博士（理学）取得 |
| 2020年4月–2021年9月 | 北海道大学化学反応創成研究拠点 博士研究員 (美多グループ) |
| 2021年10月–2022年11月 | 北海道大学化学反応創成研究拠点 特任助教 (美多グループ) |
| 2022年12月– | 名古屋大学高等研究院 兼 名古屋大学大学院 工学研究科 助教 |
| 2022年12月– | 日本学術振興会 卓越研究員 |
業績
| CV | |
|---|---|
| ORCiD | 0000-0002-0466-0116 |
| ResearcherID | N-6736-2018 |
| researchmap | 70823277 |
専門分野
有機化学、反応有機化学、計算化学
原著論文
25. Synthesis of Bicyclo[1.1.1]pentane (BCP)-Based Straight-Shaped Diphosphine Ligands
H. Takano, H. Katsuyama, H. Hayashi, M. Harukawa, M. Tsurui, S. Shoji, Y. Hasegawa, S. Maeda, T. Mita*
Angew. Chem. Int. Ed. 2023, Early View, e202303435.
Press Release (English)
24. Photoredox/HAT-Catalyzed Dearomative Nucleophilic Addition of the CO2 Radical Anion to (Hetero)Aromatics
S. R. Mangaonkar, H. Hayashi, H. Takano, W. Kanna, S. Maeda, T. Mita*
ACS Catal. 2023, 13, 2482-2488.
Press Release (English)
23. Prediction of High-Yielding Single-Step or Cascade Pericyclic Reactions for the Synthesis of Complex Synthetic Targets
T. Mita,* H. Takano, H. Hayashi, W. Kanna, Y. Harabuchi, K. N. Houk, S. Maeda
J. Am. Chem. Soc. 2022, 50, 22985-23000.
Press Release (English)
JACS Spotlight記事に取り上げられました
Selected as Cover Picture
Science Blog, In the pipeline
22. Oxidation and Reduction Pathways in the Knowles Hydroamination via a Photoredox‐Catalyzed Radical Reaction
Y. Harabuchi, H. Hayashi, H. Takano, T. Mita, S. Maeda
Angew. Chem. Int. Ed. 2023, 62, e202211936.
Press Release (English)
21. A theory-driven synthesis of symmetric and unsymmetric 1,2-bis(diphenylphosphino)ethane analogues via radical difunctionalization of ethylene
H. Takano, H. Katsuyama, H. Hayashi, W. Kanna, Y. Harabuchi, S. Maeda, T. Mita
Nat. Commun. 2022, 13, 7034.
Press Release (English)
Nature Portfolio, Behind the Paper
Chem-Stationスポットライトリサーチ
20. Experimental and Theoretical Evidence for Relativistic Catalytic Activity in C–H Activation of N-Phenylbenzamide Using a Cationic Iridium Complex
C. Takashima, H. Kurita, H. Takano, Y. Ikabata, T. Shibata, H. Nakai
J. Phys. Chem. A 2022, 126, 7627-7638.
19. In silico reaction screening with difluorocarbene for N-difluoroalkylative dearomatization of pyridines
H. Hayashi, H. Katsuyama, H. Takano, Y. Harabuchi, S. Maeda,* T. Mita*
Nat. Synth. 2022, 1, 804-814.
Press Release (English)
Nature Synthesis Research Briefing
Chem-Stationスポットライトリサーチ
18. Electrochemical Dearomative Dicarboxylation of Heterocycles with Highly Negative Reduction Potentials
Y. You, W. Kanna, H. Takano, H. Hayashi, S. Maeda,* T. Mita*
J. Am. Chem. Soc. 2022, 144, 3685-3695.
Press Release (English)
17. Radical Difunctionalization of Gaseous Ethylene Guided by Quantum Chemical Calculations: Selective Incorporation of Two Molecules of Ethylene
H. Takano, Y. You, H. Hayashi, Y. Harabuchi, S. Maeda,* T. Mita*
ACS Omega 2021, 6, 33846-33854.
16. Carboxylation of a Palladacycle Formed via C(sp3)–H Activation: Theory‐Driven Reaction Design
W. Kanna, Y. Harabuchi, H. Takano, H. Hayashi, S. Maeda,* T. Mita*
Chem. Asian J. 2021, 16, 4072-4080.
15. Synthesis of Difluoroglycine Derivatives from Amines, Difluorocarbene, and CO 2 : Computational Design, Scope, and Applications
H. Hayashi, H. Takano, H. Katsuyama, Y. Harabuchi, S. Maeda,* T. Mita*
Chem. Eur. J. 2021, 27, 10040-10047.
Selected as Front Cover
14. Pt(II)-Chiral Diene-Catalyzed Enantioselective Formal [4+2] Cycloaddition Initiated by C-C Bond Cleavage and Elucidation of a Pt(II)/(IV) Cycle by DFT Calculations
T. Shibata,* N. Shiozawa, S. Nishibe, H. Takano, S. Maeda*
Org. Chem. Front. 2021, 8, 6985-6991.
13. Gold-catalyzed dual C–C bond cleavage of biphenylenes bearing a pendant alkyne at ambient temperature
H. Takano, S. Okazaki, S. Nishibe, T. Ito, N. Shiozawa, N. Sugimura, K. S. Kanyiva, T. Shibata*
Org. Biomol. Chem. 2020, 18, 5826-5831.
12. Catalytic Enantioselective Synthesis of Axially Chiral Polycyclic Aromatic Hydrocarbons (PAHs) via Regioselective C-C Bond Activation of Biphenylenes
H. Takano, N. Shiozawa, Y. Imai, K. S. Kanyiva, T. Shibata*
J. Am. Chem. Soc. 2020, 142, 4714-4722.
Chem-Stationスポットライトリサーチ
Selected as a cover picture(Vol. 142, Issue 16)
11. Relativistic Effect on Homogeneous Catalytic Reaction by Cationic Iridium Catalysts
C. Takashima, Y. Ikabata, H. Kurita, H. Takano, T. Shibata, H. Nakai*
J. Comput. Chem. Japan 2019, 18, 136-138.
10. Consecutive HDDA and TDDA reactions of silicon-tethered tetraynes for the synthesis of dibenzosilole-fused polycyclic compounds and their unique reactivity
A. Mitake, R. Nagai, A. Sekine, H. Takano, N. Sugimura, K. S. Kanyiva, T. Shibata*
Chem. Sci. 2019, 10, 6715-6720.
9. Enantioselective Synthesis of Nine- to Eleven-Membered Cyclic Polyphenylenes Containing Heteroatoms by Catalytic Intramolecular [2+2+2] Cycloaddition
T. Shibata,* T. Fusamae, H. Takano, N. Sugimura, K. S. Kanyiva
Asian. J. Org. Chem. 2019, 8, 970-977.
8. Regioselective Activation of a Sterically More Hindered C-C Bond of Biphenylenes Using an Alkene as Both a Directing Group and a Reaction Moiety
H. Takano, T. Ito, K. S. Kanyiva, T. Shibata*
Chem. Eur. J. 2018, 24, 15173-15177.
Selected as Hot Paper
Selected as Cover Feature7. α-Amino Acid Sulfonamides as Versatile Sulfonylation Reagents: Silver-Catalyzed Synthesis of Coumarins and Oxindoles by Radical Cyclization
K. S. Kanyiva,* D. Hamada, S. Makino,H. Takano, T. Shibata*
Eur. J. Org. Chem. 2018, 83, 5905-5909.
Selected as Very Important Paper
Selected as Front Cover6. A Ir-Catalyzed Synthesis of Substituted Tribenzosilepins by Dehydrogenative C–H/Si–H Coupling
T. Shibata,* N. Uno, T. Sasaki, H. Takano, T. Sato, K. S. Kanyiva
J. Org. Chem. 2018, 83, 3426-3432.
5. DFT Studies on the Mechanism of the Iridium-Catalyzed Formal [4 + 1] Cycloaddition of Biphenylene with Alkenes
H. Takano, N. Sugimura, K. S. Kanyiva, T. Shibata*
ACS Omega 2017, 2, 5228-5234.
4. Intramolecular C-H Alkenylation of N-Alkynylindoles: Exo and Endo Selective Cyclization by the Choice of Metal Catalysts
T. Shibata,* T. Baba, H. Takano, K. S. Kanyiva
Adv. Synth. Catal. 2017, 359, 1849-1853.
Selected as Very Important Publication
3. Iridium-Catalyzed Formal [4+1] Cycloaddition of Biphenylenes with Alkenes Initiated by C-C Bond Cleavage for the Synthesis of 9,9-Disubstituted Fluorenes
H. Takano, K. S. Kanyiva, T. Shibata,*
Org. Lett. 2016, 18, 1860-1863.
2. Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates
T. Shibata,* N. Ryu, H. Takano
Adv. Synth. Catal. 2015, 357, 1131-1135.
1. Cationic iridium-catalyzed C–H alkylation of 2-substituted pyridine N-oxides with acrylates
T. Shibata,* H. Takano
Org. Chem. Front. 2015, 2, 383-387.
Selected as Very Important Publication
Selected as Inside Cover著書・総説
3. AFIR 法を用いた新規有機化学反応開発: エチレンガスのラジカル的官能基化
髙野 秀明
理論化学会誌「フロンティア」 2022, 4, 212-218.
2. 遷移金属触媒によるビフェニレン類の変換反応の開発と多環式炭化水素合成への展開
髙野 秀明, 柴田 高範
有機合成化学協会誌 2021, 79, 849-858.
