須藤雄気(Yuki Sudo)
研究課題 | 細菌ロドプシンの光エネルギー変換機構と情報伝達機構 | |
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職名 | 准教授 | ![]() |
生年月日 | 1977年10月 | |
学位 | 薬学博士 | |
最終学歴 | 北海道大学 大学院薬学系研究科 (2005) |
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専門分野 | 生物物理学 | |
分光学 | ||
生化学 | ||
分子生物学 |
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所属学会 | 日本生物物理学会・日本生化学会 | |
受賞歴 | 物理系薬学部会.フィジカルファーマーフォーラム2003(優秀ポスター賞) 財団法人光科学技術研究振興財団・平成21年度研究表彰 |
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ホームページ | http://www.geocities.co.jp/HeartLand-Asagao/4141/study.html | |
連絡先 | z47867a![]() |
欧文論文リスト
- Review: Phototactic and Chemotactic Signal Transduction by Transmembrane Receptors and Transducers in Microorganisms.
Suzuki, D., Irieda, H., Homma, M., Kawagishi, I. & Sudo, Y.
Sensors 10(4): 4010-4039. (2010) - Spectroscopic studies of a sensory rhodopsin I homolog from the archaeon Haloarcula vallismortis.
Yagasaki, J., Suzuki, D., Ihara, K., Inoue, K., Kikukawa, T., Sakai, M., Fujii, M., Homma, M., Kandori, H. & Sudo, Y.
Biochemistry 49(6):1183-1190. (2010) PubMed
- Interaction between Na+ ion and carboxylates of the PomA-PomB stator unit studied by ATR-FTIR spectroscopy.
Sudo, Y., Kitade, Y., Furutani, Y., Kojima, M., Kojima, S., Homma, M. & Kandori, H.
Biochemistry,48(49): 11699-11705. (2009) PubMed - Characterization of a signaling complex composed of sensory rhodopsin I and its cognate transducer protein from the eubacterium Salinibacter ruber.
Sudo, Y., Okada, A., Suzuki, D., Inoue, K., Irieda, H., Sakai, M., Fujii, M., Furutani, Y., Kandori, H., & Homma, M.
Biochemistry, (2009) 48(42): 10136-10145. PubMed - Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB
Kojima, S., Imada, K., Sakuma, M., Sudo, Y., Kojima, C., Minamino, T., Homma, M. & Nammba, K. Mol. Microbiol. 73: 710-718. (2009) - Effects of Chloride Ion Binding on the Photochemical Properties of Salinibacter Sensory Rhodopsin I.
Suzuki, D., Furutani, Y., Inoue, K., Kikukawa, T., Sakai, M., Fujii, M., Kandori, H., Homma, M. & Sudo, Y.
J. Mol. Biol. 392(1): 48-62. (2009) - Comparative study of the ion flux pathway in stator units of proton- and sodium-driven flagellar motors.
Sudo, Y., Terashima, H., Abe-Yoshizumi, R., Kojima, S. & Homma, M.
Biophysics,.5: 45-52. (2009)
- A photochromic photoreceptor from a eubacterium.
Suzuki, D., Kitajima-Ihara, T., Furutani, Y., Ihara, K., Kandori, H., Homma, M. & Sudo, Y.
Commun Integr Biol. 1(2):150-152. (2008) PubMed - Salinibacter sensory rhodopsin: Sensory rhodopsin I-like protein from a eubacterium.
Kitajima-Ihara, T., Furutani, Y., Suzuki, D., Ihara, K., Kandori, H., Homma, M. & Sudo, Y.
J. Biol. Chem.283(35): 23533-23541. (2008) pdf - Structural Changes of Salinibacter Sensory Rhodopsin I upon Formation of the K and M Photointermediates.
Suzuki, D., Sudo, Y., Furutani, Y., Takahashi, H., Homma, M. & Kandori, H.
Biochemistry,47(48): 12750-12759. (2008) pdf - Steric Constraint in the Primary Photoproduct of Sensory Rhodopsin II Is a Prerequisite for Light-Signal Transfer to HtrII.
Ito, M., Sudo, Y., Furutani, Y., Okitsu, T., Wada, A., Homma, M., Spudich, J.L. & Kandori, H.
Biochemistry, 47(23): 6208-6215. (2008) pdf
- A long-lived M-like state of phoborhodopsin that mimics the active state.
Sudo, Y., Nishihori, T., Iwamoto, M., Shimono, K., Kojima, C. & Kamo, N.
Biophys, J. 95: 753-760. (2008) - Protein-protein interaction of a Pharaonis halorhodopsin mutant forming a complex with Pharaonis halobacterial transducer protein II detected by Fourier-transform infrared spectroscopy.
Furutani, Y., Ito, M., Sudo, Y., Kamo, N. & Kandori, H.
Photochem Photobiol 84: 874-879. (2008) - Structural changes of sensory rhodopsin I and its transducer protein are dependent on the protonated state of Asp76
Furutani, Y., Takahashi, H., Sasaki, J., Sudo, Y., Spudich, J.L. & Kandori, H.
Biochemistry 47: 2875-2883. (2008) - Structral changes in the O-decay accelerated mutants of pharaonis phoborhodopsin
Sudo, Y., Furutani, Y., Iwamoto, M., Kamo, N. & Kandori, H.
Biochemistry 47: 2866-2874. (2008)
- Structural analysis of the phototactic transducer protein HtrII linker region from Natronomonas pharaonis
Hayashi, K., Sudo, Y., Jee, J., Mishima, M., Hara, H., Kamo, N. & Kojima, C.
Biochemistry 46: 14380-14390. (2007) - Early photocycle structural changes in a bacteriorhodopsin mutant engineered to transmit photosensory signals
Sudo, Y., Furutani, Y., Spudich, J.L. & Kandori, H.
J. Biol. Chem. 282: 15550-15558. (2007) - Participation of the surface structure of pharaonis phoborhodopsin, ppR and its A149S and A149V mutants, consisting of the C-terminal alpha-helix and E-F loop, in the complex-formation with the cognate transducer pHtrII, as revealed by site-directed (13)C solid-state NMR
Kawamura, I., Ikeda, Y., Sudo, Y., Iwamoto, M., Shimono, K., Yamaguchi, S., Tuzi, S., Saito, H., Kamo, N. & Naito, A.
Photochem. Photobiol. 83: 339-345. (2007) - Interaction of the halobacterial transducer to a halorhodopsin mutant engineered so as to bind the transducer: Cl- circulation within the extracellular channel
Hasegawa, C., Kikukawa, T., Miyauchi, S., Seki, A., Sudo, Y., Kubo, M., Demura, M. & Kamo, N.
Photochem. Photobiol. 83: 293-302. (2007)
- Three strategically placed hydrogen-bonding residues convert a proton pump into a sensory receptor
Sudo, Y. & Spudich, J.L.
Proc. Natl. Acad. Sci. USA 103: 16129-16134. (2006) - Assignment of the Hydrogen-Out-Of-Plane and In-Plane vibrations of the retinal chromophore in the K intermediate of pharaonis phoborhodopsin
Furutani, Y., Sudo, Y., Wada, A., Ito, M, Shimono, K., Kamo, N. & Kandori, H.
Biochemistry 45: 11836-11843. (2006) - Functional importance of the interhelical hydrogen bond between Thr204 and Tyr174 of sensory rhodopsin II and its alteration during the signaling process
Sudo, Y., Furutani, Y., Kandori, H. & Spudich, J.L.
J. Biol. Chem. 281: 34239-34245. (2006) - Temperature-dependent interactions between photoactivated pharaonis phoborhodopsin and its transducer
Kamada, K., Furutani, Y., Sudo, Y., Kamo, N. & Kandori, H.
Biochemistry 45: 4859-4866. (2006) - Importance of the specific hydrogen bonds of archaeal rhodopsins for the binding to the transducer protein
Sudo, Y., Yamabi, M., Kato, S., Hasegawa, C., Iwamoto, M., Shimono, K. & Kamo, N.
J. Mol. Biol. 357: 1274-1282. (2006)
- Steric constraint in the primary photoproduct of an archaeal rhodopsin from regiospecific perturbation of C-D stretching vibration of the retinyl chromophore
Sudo, Y., Furutani, Y., Wada, A., Ito, M., Kamo, N. & Kandori, H.
J. Am. Chem. Soc. 127: 16036-16037. (2005) - Linker region of a halobacterial transducer protein interacts directly with its sensor retinal protein
Sudo, Y., Okuda, H., Yamabi, M., Fukuzaki, Y., Mishima, M., Kamo, N. & Kojima, C.
Biochemistry 44: 6144-6152. (2005) - Correlation of the O-intermediate rate with the pka of Asp-75 in the dark, the counterion of the Schiff base of pharaonis phoborhodopsin (Sensory rhodopsin II)
Iwamoto, M., Sudo, Y., Shimono, K., Araiso, T. & Kamo, N.
Biophys. J. 88: 1215-1223. (2005) - Structural changes of the complex between pharaonis phoborhodopsin and its cognate transducer upon formation of the M photointermediate
Furutani, Y., Kamada, K., Sudo, Y., Shimono, K., Kamo, N. & Kandori, H.
Biochemistry 44: 2909-2915. (2005)
- Role of charged residues of pharaonis phoborhodopsin (sensory rhodopsin II) in its interaction with the transducer protein
Sudo, Y., Iwamoto, M., Shimono, K. & Kamo, N.
Biochemistry 43: 13748-13754. (2004) - Transient movement of Helix-F revealed from photo-induced inactivation by reaction of a bulky SH-reagent to cysteine-induced pharaonis phoborhodopsin (sensory rhodopsin II)
Yoshida, H., Sudo, Y., Iwamoto, M., Shimono, K. & Kamo, N.
Photochem. Phobiol. Sci. 3: 537-542. (2004) - Conformation and dynamics of [3-13C]Ala-, [1-13C]Val-labeled truncated pharaonis transducer, pHtrII(1-159) as revealed by site-directed 13C Solid-state NMR: Their changes due to association with phoborhodopsin (sensory rhodopsin II)
Yamaguchi, S., Shimono, K., Sudo, Y., Tuzi, S., Naito, A., Kamo, N. & Saito, H.
Biophys. J. 86: 3131-3140. (2004) - Role of Arg-72 of pharaonis phoborhodopsin (sensory rhodopsin II) on its photochemistry
Ikeura, Y., Shimono, K., Iwamoto, M., Sudo, Y. & Kamo, N.
Biophys. J. 86: 3112-3120. (2004) - Proton release and uptake of pharaonis phoborhodopsin (sensory rhodopsin II) reconstituted into phospholipids
Iwamoto, M., Hasegawa, C., Sudo, Y., Shimono, K., Araiso, T. & Kamo, N.
Biochemistry 43: 3195-3203. (2004)
- Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein
Sudo, Y., Furutani, Y., Shimono, K., Kamo, N. & Kandori, H.
Biochemistry 42: 14166-14172. (2003) - Inrteraction of Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II) with its cognate transducer probed by increase in the thermal stability
Sudo, Y., Yamabi, M., Iwamoto, M., Shimono, K. & Kamo, N.
Photochem. Photobiol. 78: 511-516. (2003) - Importance of the broad regional interaction for spectral tuning in Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II)
Shimono, K., Hayashi, T., Ikeura, Y., Sudo, Y., Iwamoto, M. & Kamo, N.
J. Biol. Chem. 278: 23882-23889. (2003) - FTIR spectroscopy of the complex between pharaonis phoborhodopsin and its transducer protein
Furutani, Y., Sudo, Y., Kamo, N. & Kandori, H.
Biochemistry 42: 4837-4842. (2003) - Dynamic structure of pharoanis phoborhodopsin (sensory rhodopsin II) and complex with a cognate truncated transucer as revealed by site-directed 13C solid state NMR
Arakawa, T., Shimono, K., Yamaguchi, S., Tuzi, S., Sudo, Y., Kamo, N. & Saito, H.
FEBS Lett. 536: 237-240. (2003) - Arg-72 of pharaonis phoborhodopsin (sensory rhodopsin II) is important for the maintenance of the protein structure in the solubilized state
Ikeura, Y., Shimono, K., Iwamoto, M., Sudo, Y. & Kamo, N.
Photochem. Photobiol. 77: 96-100. (2003)
総説
- Molecular mechanism of protein-protein interaction of pharaonis phoborhodopsin/transducer and photo-signal transfer reaction by the complex
Sudo, Y., Kandori, H. & Kamo, N.
Recent Res. Devel. Biophys. 3: 1-16. (2004)
邦文著作リスト
- 須藤雄気
光駆動イオンポンプから光情報伝達への機能変換の試み
生物物理 46, 330-335. (2006) - 須藤雄気, 河野俊之, 児嶋長次郎
無細胞タンパク質合成系を用いた膜タンパク質発現の新規手法
実験医学 23, 1933-1937. (2005) - 須藤雄気, 河野俊之, 田中利好, 加茂直樹, 児嶋長次郎
膜蛋白質の機能的大量発現
遺伝子医学MOCK別冊 「図・写真で観るタンパク質構造・機能解析実験実践ガイド」 41-46. (2005)