トップ構成員>須藤雄気

須藤雄気(Yuki Sudo)

研究課題 細菌ロドプシンの光エネルギー変換機構と情報伝達機構
職名 准教授
須藤雄気助教
生年月日 1977年10月
学位 薬学博士
最終学歴 北海道大学
大学院薬学系研究科
(2005) 
専門分野 生物物理学
分光学
生化学
分子生物学
所属学会 日本生物物理学会・日本生化学会
受賞歴 物理系薬学部会.フィジカルファーマーフォーラム2003(優秀ポスター賞)
財団法人光科学技術研究振興財団・平成21年度研究表彰
ホームページ http://www.geocities.co.jp/HeartLand-Asagao/4141/study.html
連絡先 z47867acc.nagoya-u.ac.jp

欧文論文リスト

2010

  • Review: Phototactic and Chemotactic Signal Transduction by Transmembrane Receptors and Transducers in Microorganisms.
    Suzuki, D., Irieda, H., Homma, M., Kawagishi, I. & Sudo, Y.
    Sensors 10(4): 4010-4039. (2010)
  • Spectroscopic studies of a sensory rhodopsin I homolog from the archaeon Haloarcula vallismortis.
    Yagasaki, J., Suzuki, D., Ihara, K., Inoue, K., Kikukawa, T., Sakai, M., Fujii, M., Homma, M., Kandori, H. & Sudo, Y.
    Biochemistry 49(6):1183-1190. (2010) PubMed

2009

  • Interaction between Na+ ion and carboxylates of the PomA-PomB stator unit studied by ATR-FTIR spectroscopy.
    Sudo, Y., Kitade, Y., Furutani, Y., Kojima, M., Kojima, S., Homma, M. & Kandori, H.
    Biochemistry,48(49): 11699-11705. (2009) PubMed
  • Characterization of a signaling complex composed of sensory rhodopsin I and its cognate transducer protein from the eubacterium Salinibacter ruber.
    Sudo, Y., Okada, A., Suzuki, D., Inoue, K., Irieda, H., Sakai, M., Fujii, M., Furutani, Y., Kandori, H., & Homma, M.
    Biochemistry, (2009) 48(42): 10136-10145. PubMed
  • Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB
    Kojima, S., Imada, K., Sakuma, M., Sudo, Y., Kojima, C., Minamino, T., Homma, M. & Nammba, K. Mol. Microbiol. 73: 710-718. (2009)
  • Effects of Chloride Ion Binding on the Photochemical Properties of Salinibacter Sensory Rhodopsin I.
    Suzuki, D., Furutani, Y., Inoue, K., Kikukawa, T., Sakai, M., Fujii, M., Kandori, H., Homma, M. & Sudo, Y.
    J. Mol. Biol. 392(1): 48-62. (2009)
  • Comparative study of the ion flux pathway in stator units of proton- and sodium-driven flagellar motors.
    Sudo, Y., Terashima, H., Abe-Yoshizumi, R., Kojima, S. & Homma, M.
    Biophysics
    ,.5: 45-52. (2009)

2008

  • A photochromic photoreceptor from a eubacterium.
    Suzuki, D., Kitajima-Ihara, T., Furutani, Y., Ihara, K., Kandori, H., Homma, M. & Sudo, Y.
    Commun Integr Biol. 1(2):150-152. (2008) PubMed
  • Salinibacter sensory rhodopsin: Sensory rhodopsin I-like protein from a eubacterium.
    Kitajima-Ihara, T., Furutani, Y., Suzuki, D., Ihara, K., Kandori, H., Homma, M. & Sudo, Y.
    J. Biol. Chem.283(35): 23533-23541. (2008) pdf
  • Structural Changes of Salinibacter Sensory Rhodopsin I upon Formation of the K and M Photointermediates.
    Suzuki, D., Sudo, Y., Furutani, Y., Takahashi, H., Homma, M. & Kandori, H.
    Biochemistry,47(48): 12750-12759. (2008) pdf
  • Steric Constraint in the Primary Photoproduct of Sensory Rhodopsin II Is a Prerequisite for Light-Signal Transfer to HtrII.
    Ito, M., Sudo, Y., Furutani, Y., Okitsu, T., Wada, A., Homma, M., Spudich, J.L. & Kandori, H.
    Biochemistry, 47(23): 6208-6215. (2008) pdf
  • A long-lived M-like state of phoborhodopsin that mimics the active state.
    Sudo, Y., Nishihori, T., Iwamoto, M., Shimono, K., Kojima, C. & Kamo, N.
    Biophys, J. 95: 753-760. (2008)
  • Protein-protein interaction of a Pharaonis halorhodopsin mutant forming a complex with Pharaonis halobacterial transducer protein II detected by Fourier-transform infrared spectroscopy.
    Furutani, Y., Ito, M., Sudo, Y., Kamo, N. & Kandori, H.
    Photochem Photobiol 84: 874-879. (2008)
  • Structural changes of sensory rhodopsin I and its transducer protein are dependent on the protonated state of Asp76
    Furutani, Y., Takahashi, H., Sasaki, J., Sudo, Y., Spudich, J.L. & Kandori, H.
    Biochemistry 47: 2875-2883. (2008)
  • Structral changes in the O-decay accelerated mutants of pharaonis phoborhodopsin
    Sudo, Y., Furutani, Y., Iwamoto, M., Kamo, N. & Kandori, H.
    Biochemistry 47: 2866-2874. (2008)

2007

  • Structural analysis of the phototactic transducer protein HtrII linker region from Natronomonas pharaonis
    Hayashi, K., Sudo, Y., Jee, J., Mishima, M., Hara, H., Kamo, N. & Kojima, C.
    Biochemistry 46: 14380-14390. (2007)
  • Early photocycle structural changes in a bacteriorhodopsin mutant engineered to transmit photosensory signals
    Sudo, Y., Furutani, Y., Spudich, J.L. & Kandori, H.
    J. Biol. Chem. 282: 15550-15558. (2007)
  • Participation of the surface structure of pharaonis phoborhodopsin, ppR and its A149S and A149V mutants, consisting of the C-terminal alpha-helix and E-F loop, in the complex-formation with the cognate transducer pHtrII, as revealed by site-directed (13)C solid-state NMR
    Kawamura, I., Ikeda, Y., Sudo, Y., Iwamoto, M., Shimono, K., Yamaguchi, S., Tuzi, S., Saito, H., Kamo, N. & Naito, A.
    Photochem. Photobiol. 83: 339-345. (2007)
  • Interaction of the halobacterial transducer to a halorhodopsin mutant engineered so as to bind the transducer: Cl- circulation within the extracellular channel
    Hasegawa, C., Kikukawa, T., Miyauchi, S., Seki, A., Sudo, Y., Kubo, M., Demura, M. & Kamo, N.
    Photochem. Photobiol. 83: 293-302. (2007)

2006

  • Three strategically placed hydrogen-bonding residues convert a proton pump into a sensory receptor
    Sudo, Y. & Spudich, J.L.
    Proc. Natl. Acad. Sci. USA 103: 16129-16134. (2006)
  • Assignment of the Hydrogen-Out-Of-Plane and In-Plane vibrations of the retinal chromophore in the K intermediate of pharaonis phoborhodopsin
    Furutani, Y., Sudo, Y., Wada, A., Ito, M, Shimono, K., Kamo, N. & Kandori, H.
    Biochemistry 45: 11836-11843. (2006)
  • Functional importance of the interhelical hydrogen bond between Thr204 and Tyr174 of sensory rhodopsin II and its alteration during the signaling process
    Sudo, Y., Furutani, Y., Kandori, H. & Spudich, J.L.
    J. Biol. Chem. 281: 34239-34245. (2006)
  • Temperature-dependent interactions between photoactivated pharaonis phoborhodopsin and its transducer
    Kamada, K., Furutani, Y., Sudo, Y., Kamo, N. & Kandori, H.
    Biochemistry 45: 4859-4866. (2006)
  • Importance of the specific hydrogen bonds of archaeal rhodopsins for the binding to the transducer protein
    Sudo, Y., Yamabi, M., Kato, S., Hasegawa, C., Iwamoto, M., Shimono, K. & Kamo, N.
    J. Mol. Biol. 357: 1274-1282. (2006)

2005

  • Steric constraint in the primary photoproduct of an archaeal rhodopsin from regiospecific perturbation of C-D stretching vibration of the retinyl chromophore
    Sudo, Y., Furutani, Y., Wada, A., Ito, M., Kamo, N. & Kandori, H.
    J. Am. Chem. Soc. 127: 16036-16037. (2005)
  • Linker region of a halobacterial transducer protein interacts directly with its sensor retinal protein
    Sudo, Y., Okuda, H., Yamabi, M., Fukuzaki, Y., Mishima, M., Kamo, N. & Kojima, C.
    Biochemistry 44: 6144-6152. (2005)
  • Correlation of the O-intermediate rate with the pka of Asp-75 in the dark, the counterion of the Schiff base of pharaonis phoborhodopsin (Sensory rhodopsin II)
    Iwamoto, M., Sudo, Y., Shimono, K., Araiso, T. & Kamo, N.
    Biophys. J. 88: 1215-1223. (2005)
  • Structural changes of the complex between pharaonis phoborhodopsin and its cognate transducer upon formation of the M photointermediate
    Furutani, Y., Kamada, K., Sudo, Y., Shimono, K., Kamo, N. & Kandori, H.
    Biochemistry 44: 2909-2915. (2005)

2004

  • Role of charged residues of pharaonis phoborhodopsin (sensory rhodopsin II) in its interaction with the transducer protein
    Sudo, Y., Iwamoto, M., Shimono, K. & Kamo, N.
    Biochemistry 43: 13748-13754. (2004)
  • Transient movement of Helix-F revealed from photo-induced inactivation by reaction of a bulky SH-reagent to cysteine-induced pharaonis phoborhodopsin (sensory rhodopsin II)
    Yoshida, H., Sudo, Y., Iwamoto, M., Shimono, K. & Kamo, N.
    Photochem. Phobiol. Sci. 3: 537-542. (2004)
  • Conformation and dynamics of [3-13C]Ala-, [1-13C]Val-labeled truncated pharaonis transducer, pHtrII(1-159) as revealed by site-directed 13C Solid-state NMR: Their changes due to association with phoborhodopsin (sensory rhodopsin II)
    Yamaguchi, S., Shimono, K., Sudo, Y., Tuzi, S., Naito, A., Kamo, N. & Saito, H.
    Biophys. J. 86: 3131-3140. (2004)
  • Role of Arg-72 of pharaonis phoborhodopsin (sensory rhodopsin II) on its photochemistry
    Ikeura, Y., Shimono, K., Iwamoto, M., Sudo, Y. & Kamo, N.
    Biophys. J. 86: 3112-3120. (2004)
  • Proton release and uptake of pharaonis phoborhodopsin (sensory rhodopsin II) reconstituted into phospholipids
    Iwamoto, M., Hasegawa, C., Sudo, Y., Shimono, K., Araiso, T. & Kamo, N.
    Biochemistry 43: 3195-3203. (2004)

2003

  • Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein
    Sudo, Y., Furutani, Y., Shimono, K., Kamo, N. & Kandori, H.
    Biochemistry 42: 14166-14172. (2003)
  • Inrteraction of Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II) with its cognate transducer probed by increase in the thermal stability
    Sudo, Y., Yamabi, M., Iwamoto, M., Shimono, K. & Kamo, N.
    Photochem. Photobiol. 78: 511-516. (2003)
  • Importance of the broad regional interaction for spectral tuning in Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II)
    Shimono, K., Hayashi, T., Ikeura, Y., Sudo, Y., Iwamoto, M. & Kamo, N.
    J. Biol. Chem. 278: 23882-23889. (2003)
  • FTIR spectroscopy of the complex between pharaonis phoborhodopsin and its transducer protein
    Furutani, Y., Sudo, Y., Kamo, N. & Kandori, H.
    Biochemistry 42: 4837-4842. (2003)
  • Dynamic structure of pharoanis phoborhodopsin (sensory rhodopsin II) and complex with a cognate truncated transucer as revealed by site-directed 13C solid state NMR
    Arakawa, T., Shimono, K., Yamaguchi, S., Tuzi, S., Sudo, Y., Kamo, N. & Saito, H.
    FEBS Lett. 536: 237-240. (2003)
  • Arg-72 of pharaonis phoborhodopsin (sensory rhodopsin II) is important for the maintenance of the protein structure in the solubilized state
    Ikeura, Y., Shimono, K., Iwamoto, M., Sudo, Y. & Kamo, N.
    Photochem. Photobiol. 77: 96-100. (2003)

総説

  • Molecular mechanism of protein-protein interaction of pharaonis phoborhodopsin/transducer and photo-signal transfer reaction by the complex
    Sudo, Y., Kandori, H. & Kamo, N.
    Recent Res. Devel. Biophys. 3: 1-16. (2004)

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